中国科学院上海生命科学研究院神经科学研究所机构知识库
Advanced  
SIBS OpenIR  > 神经所(总)  > 期刊论文
Title: Synapse formation and remodeling
Author: Luo ZhenGe
Source: SCIENCE CHINA-LIFE SCIENCES
Issued Date: 2010
Volume: 53, Issue:3, Pages:315-321
Keyword: synapse development ; neuronal activity ; synaptic plasticity ; VERTEBRATE NEUROMUSCULAR-JUNCTION ; AMPA RECEPTOR TRAFFICKING ; LONG-TERM POTENTIATION ; ACETYLCHOLINE-RECEPTOR ; PDZ-DOMAIN ; GERANYLGERANYLTRANSFERASE-I ; CHOLINE-ACETYLTRANSFERASE ; TARGET BINDING ; AGRIN ; RAPSYN
Subject: Life Sciences & Biomedicine - Other Topics
Corresponding Author: Luo, ZG (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Neurosci, Shanghai 200031, Peoples R China,zgluo@ion.ac.cn
English Abstract: Synapses are specialized structures that mediate information flow between neurons and target cells, and thus are the basis for neuronal system to execute various functions, including learning and memory. There are around 10(11) neurons in the human brain, with each neuron receiving thousands of synaptic inputs, either excitatory or inhibitory. A synapse is an asymmetric structure that is composed of pre-synaptic axon terminals, synaptic cleft, and postsynaptic compartments. Synapse formation involves a number of cell adhesion molecules, extracellular factors, and intracellular signaling or structural proteins. After the establishment of synaptic connections, synapses undergo structural or functional changes, known as synaptic plasticity which is believed to be regulated by neuronal activity and a variety of secreted factors. This review summarizes recent progress in the field of synapse development, with particular emphasis on the work carried out in China during the past 10 years (1999-2009).
Indexed Type: sci
Language: 英语
Content Type: 期刊论文
URI: http://ir.sibs.ac.cn/handle/331001/1607
Appears in Collections:神经所(总)_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Luo-2010-Synapse formation an.pdf(975KB)----开放获取View Download

Recommended Citation:
Luo ZhenGe.Synapse formation and remodeling,SCIENCE CHINA-LIFE SCIENCES,2010,53(3):315-321
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Luo ZhenGe]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Luo ZhenGe]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Luo-2010-Synapse formation an.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!