中国科学院上海生命科学研究院神经科学研究所机构知识库
Advanced  
SIBS OpenIR  > 神经所(总)  > 期刊论文
Title: Entrainment of Slow Oscillations of Auditory Thalamic Neurons by Repetitive Sound Stimuli
Author: Gao, Lixia ; Meng, Xiankai ; Ye, Changquan ; Zhang, Haitian ; Liu, Chunhua ; Dan, Yang ; null(蒲慕明) ; He, Jufang ; Zhang, Xiaohui
Source: JOURNAL OF NEUROSCIENCE
Issued Date: 2009
Volume: 29, Issue:18, Pages:6013-6021
Keyword: LESS-THAN-1 HZ OSCILLATION ; NETWORK MECHANISMS ; PURKINJE-CELLS ; SPINY NEURONS ; IN-VIVO ; CORTEX ; SLEEP ; FLUCTUATIONS ; BISTABILITY ; VARIABILITY
Subject: Neurosciences & Neurology
Corresponding Author: He, JF (reprint author), Hong Kong Polytech Univ, Dept Rehabil Sci, Kowloon, Hong Kong, Peoples R China,Jufang.He@inet.polyu.edu.hk ; xhzhang@ion.ac.cn
English Abstract: Slow oscillations at frequencies <1 Hz manifest in many brain regions as discrete transitions between a depolarized up state and a hyperpolarized down state of the neuronal membrane potential. Although up and down states are known to differentially affect sensory-evoked responses, whether and how they are modulated by sensory stimuli are not well understood. In the present study, intracellular recording in anesthetized guinea pigs showed that membrane potentials of nonlemniscal auditory thalamic neurons exhibited spontaneous up/down transitions at random intervals in the range of 2-30 s, which could be entrained to a regular interval by repetitive sound stimuli. After termination of the entraining stimulation (ES), regular up/down transitions persisted for several cycles at the ES interval. Furthermore, the efficacy of weak sound stimuli in triggering the up-to-down transition was potentiated specifically at the ES interval for at least 10 min. Extracellular recordings in the auditory thalamus of unanesthetized guinea pigs also showed entrainment of slow oscillations by rhythmic sound stimuli during slow wave sleep. These results demonstrate a novel form of network plasticity, which could help to retain the information of stimulus interval on the order of seconds.
Indexed Type: sci
Language: 英语
Content Type: 期刊论文
URI: http://ir.sibs.ac.cn/handle/331001/1659
Appears in Collections:神经所(总)_期刊论文
神经可塑性研究组_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Gao-2009-Entrainment of Slow.pdf(713KB)----开放获取View Download

Recommended Citation:
Gao, Lixia; Meng, Xiankai; Ye, Changquan; Zhang, Haitian; Liu, Chunhua; Dan, Yang; Poo, Mu-ming; He, Jufang; Zhang, Xiaohui.Entrainment of Slow Oscillations of Auditory Thalamic Neurons by Repetitive Sound Stimuli,JOURNAL OF NEUROSCIENCE,2009,29(18):6013-6021
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Gao, Lixia]'s Articles
[Meng, Xiankai]'s Articles
[Ye, Changquan]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Gao, Lixia]‘s Articles
[Meng, Xiankai]‘s Articles
[Ye, Changquan]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Gao-2009-Entrainment of Slow.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!