中国科学院上海生命科学研究院神经科学研究所机构知识库
Advanced  
SIBS OpenIR  > 神经所(总)  > 期刊论文
Title: Identification and two-photon imaging of oligodendrocyte in CA1 region of hippocampal slices
Author: Zhou, Wei ; Ge, Woo-Ping ; Zeng, Shaoqun ; Duan, Shumin ; Luo, Qingming
Source: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Issued Date: 2007
Volume: 352, Issue:3, Pages:598-602
Keyword: oligodendrocyte ; whole-cell recording ; two-photon laser scanning microscopy ; CA1 region ; hippocampal slice ; LONG-TERM POTENTIATION ; TRANSPORTER CURRENTS ; GLUTAMATE RELEASE ; DENDRITIC SPINES ; NMDA RECEPTORS ; GLIAL CALCIUM ; ASTROCYTES ; SYNAPSES ; CELLS ; LTP
Subject: Biochemistry & Molecular Biology ; Biophysics
Corresponding Author: Luo, QM (reprint author), Huazhong Univ Sci & Technol, Key Lab Biomed Photon, Minist Educ, Wuhan Natl Lab Optoelect, Wuhan 430074, Peoples R China,qluo@mail.hust.edu.cn
English Abstract: Oligodendrocyte (OL) plays a critical role in myelination and axon maintenance in central nervous system. Recent studies show that OL can also express NMDA receptors in development and pathological situations in white matter. There is still lack of studies about OL properties and function in gray matter of brain. Here we reported that some glial cells in CA1 region of rat hippocampal slices (P15-23) had distinct electrophysiological characteristics from the other glia cells in this region, while they displayed uniform properties with OL from white matter in previous report; therefore, they were considered as OL in hippocampus. By loading dye in recording pipette and imaging with two-photon laser scanning microscopy, we acquired the high spatial resolution, three-dimension images of these special cells in live slices. The OL in hippocampus shows a complex process-bearing shape and the distribution of several processes is parallel to Schaffer fiber in CA1 region. When stimulating Schaffer fiber, OL displays a long duration depolarization mediated by inward rectifier potassium channel. This suggested that the OL in CA1 region could sense the neuronal activity and contribute to potassium clearance. (c) 2006 Elsevier Inc. All rights reserved.
Indexed Type: sci
Language: 英语
Content Type: 期刊论文
URI: http://ir.sibs.ac.cn/handle/331001/1790
Appears in Collections:神经所(总)_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
1-s2.0-S0006291X06025162-main.pdf(641KB)----开放获取View Download

Recommended Citation:
Zhou, Wei; Ge, Woo-Ping; Zeng, Shaoqun; Duan, Shumin; Luo, Qingming.Identification and two-photon imaging of oligodendrocyte in CA1 region of hippocampal slices,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2007,352(3):598-602
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhou, Wei]'s Articles
[Ge, Woo-Ping]'s Articles
[Zeng, Shaoqun]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhou, Wei]‘s Articles
[Ge, Woo-Ping]‘s Articles
[Zeng, Shaoqun]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 1-s2.0-S0006291X06025162-main.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!